Application Rule Order

Rules with application conditions are more likely to match traffic if you move them to a lower order in your list of rules.

Access control rules that use specific conditions (such as networks and IP addresses) should be ordered before rules that use general conditions (such as applications). If you're familiar with the Open Systems Interconnect (OSI) model, use similar numbering in concept. Rules with conditions for layers 1, 2, and 3 (physical, data link, and network) should be ordered first in your access control rules. Conditions for layers 5, 6, and 7 (session, presentation, and application) should be ordered later in your access control rules. For more information about the OSI model, see this Wikipedia article.

For more information and an example, see Best Practices for Configuring Application Control and Recommendations for Application Control.