Requirements for Dynamic Analysis

You must be an Admin, Access Admin, or Network Admin user, and be in the global domain, to use dynamic analysis.

With the appropriate license, the system automatically has access to the Secure Malware Analytics Cloud.

Dynamic analysis requires that managed devices have direct or proxied access to the Secure Malware Analytics Cloud or an on-premises Secure Malware Analytics Appliance on port 443.

See also Which Files Are Eligible for Dynamic Analysis?.